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Insulin Degludec

Uses

Insulin Degludec is used in the treatment of diabetes.

How it Works

How Insulin Degludec Works Insulin Degludec is a long-acting insulin that provides consistent, all-day blood sugar control. It functions similarly to the body's natural insulin. Insulin facilitates the uptake of glucose in muscle and fat cells while suppressing glucose production in the liver.

Side Effects

Common side effects of Insulin Degludec include severe hypoglycemia, auto-antibody formation, headache, nasopharyngitis (inflammation of the throat and nasal passages), and upper respiratory tract infection.

Expert Advice

This medicine is injected subcutaneously.
It must be administered once daily, at the same time each day.
Injecting into the abdomen allows for faster absorption compared to other injection sites.
Injection sites should be rotated to prevent the development of hard lumps.
Do not use the preparation if it is no longer clear and colorless or if it contains particles.
Hypoglycemia (low blood sugar level) is a common side effect.
Always carry sugary food or fruit juice to manage hypoglycemia symptoms, which may include:

Cold sweats
Cool, pale skin
Tremors
Anxiety

Opened vials or cartridges remain stable at room temperature for up to 4 weeks.
Unopened vials should be stored in the refrigerator (2°C–8°C).

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Salt Composition

100IU | Insulin Degludec 2.56mg + Insulin Aspart 1.05mg

Ryzodeg 2.56/1.05mg (100 IU/ml) (1*3ml Penfill Cartridge / Injection)

Novo Nordisk India Pvt. Ltd.

Cartridge of 3 ml

₹1,077.6

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MRP ₹1,238.6

Salt Composition in both

Insulin Degludec 2.56mg/ml + Insulin Aspart 1.05mg/ml

Ryzodeg 100 unit/ml Penfill (3ml Each)

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box of 5

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₹6,193

Ryzodeg 2.56/1.05mg (100 IU/ml) (1*3ml Penfill Cartridge / Injection)

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Cartridge of 3 ml

₹1,077.6

MRP ₹1,238.6

71% OFF

Salt Composition

Insulin Degludec 2.56mg + Insulin Aspart 1.05mg

Ryzodeg 100IU/ml Flextouch

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Pre-filled Pen of 3 ml

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MRP ₹1,595

Salt Composition in both

Insulin Degludec 100IU

Tresiba 100 Units/ml Penfill (3ml Each)

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₹7,200

Tresiba (100 IU/ml) (1*3ml Cartridge / Injection)

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₹1,252.8

MRP ₹1,440

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Salt Composition

Insulin Degludec 100IU

Tresiba (100 IU/ml) (1*3ml Cartridge / Injection)

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₹1,252.8

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MRP ₹1,440

Salt Composition

Insulin Degludec 100IU

Tresiba (100 IU/ml) (1*3ml Flextouch Pen)

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Disposable Pen of 3 ml

₹1,689.5

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MRP ₹1,942

Salt Composition

100 IU | Liraglutide 3.6mg + Insulin Degludec 100mg

Xultophy 3.6/100mg (100 IU/ml) (5*3ml Disposable Pen)

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₹4,703

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MRP ₹5,735.4

Frequently asked questions

What is Insulin Degludec?

Insulin Degludec is an ultra-long-acting insulin used to manage high blood sugar in adults and children (from 1 year old) with type 1 and type 2 diabetes. It mimics natural insulin, facilitating the movement of sugar from the blood into tissues for energy and inhibiting liver sugar production to stabilize blood sugar levels.

Can Insulin Degludec be used alone?

Insulin Degludec can effectively manage daily diabetes control. However, short-acting insulin or oral medications may be prescribed for post-meal blood sugar spikes. Follow your doctor's guidance for optimal blood sugar management.

How is Insulin Degludec administered?

Insulin Degludec is injected subcutaneously. Your doctor will instruct you on proper injection techniques and sites (abdomen, thighs, arms, hips, or buttocks). Rotate injection sites within the chosen area to prevent complications like lipodystrophy. After 1-2 weeks, switch to another body area as recommended by your doctor. Consult your doctor for any injection-related issues.

Can Insulin Degludec cause weight gain?

Yes, Insulin Degludec may cause weight gain in some patients due to its anabolic effects, which promote glucose and fat storage.

Can Insulin Degludec raise your blood sugar?

No, Insulin Degludec does not raise blood sugar by itself. However, missing doses or taking lower doses can lead to increased blood sugar levels. Other factors like infections, stress, irregular meals, or reduced activity can also elevate blood sugar. Consult your doctor regarding dosage adjustments if you face these issues.

Is Insulin Degludec better than Insulin Detemir?

Both Insulin Degludec and Insulin Detemir are long-acting insulins with similar effectiveness and safety. The key difference is that Insulin Degludec has a longer duration of action (over 40 hours), which helps maintain stable blood sugar levels and may pose a slightly lower risk of hypoglycemia.

What should I avoid while taking Insulin Degludec?

Avoid missing doses and adhere to your prescribed diabetic diet. Consult a dietitian for a suitable meal plan. Maintain an active lifestyle and follow your doctor's recommendations. Avoid driving or operating heavy machinery until you know how Insulin Degludec affects you, and limit alcohol consumption as it can impact blood sugar. Regularly monitor your blood sugar levels and attend all doctor appointments.

Is Insulin Degludec a basal insulin? How does it work?

Yes, Insulin Degludec is a basal insulin, providing long-acting background insulin coverage for over 24 hours to help maintain stable blood sugar levels throughout the day.

Do I have to take Insulin Degludec at the same time every day?

Yes, it is recommended to take Insulin Degludec at the same time daily as prescribed. If necessary, it can be taken at different times, but maintain a minimum 8-hour gap between doses. Children and young adults should take it at the same time every day.

Can Insulin Degludec be used in combination with other diabetes medicines?

Insulin Degludec can be safely combined with other diabetes medications or fast-acting insulin as prescribed. However, caution is advised when using thiazolidinediones (TZDs) like pioglitazone, as they may increase the risk of heart failure. Inform your doctor about all medications and any history of heart problems.